What is the difference between omeprazole and famotidine

Omeprazole is usually taken once daily. Famotidine and omeprazole can be prescribed to treat GERD, duodenal ulcers, and stomach ulcers.

Both medications are also FDA-approved to treat erosive esophagitis EE , or inflammation of the lining in the esophagus. Erosive esophagitis is often caused by GERD. Prescription famotidine and omeprazole can also be used to treat hypersecretory conditions, such as Zollinger-Ellison syndrome. These drugs can help reduce stomach acid caused by rare disorders. Sign up for Famotidine price alerts and find out when the price changes! Get Price Alerts. Over-the-counter OTC versions of famotidine and omeprazole can be used for the relief of occasional or frequent heartburn.

Acid reflux, which occurs when stomach acid gets backed up into the esophagus, is a common cause of heartburn. The bacteria that cause this infection attacks the stomach lining, which can result in peptic ulcers. Treatment includes omeprazole combined with an antibiotic like amoxicillin or clarithromycin. Both famotidine and omeprazole can be effective drugs for treating GERD and other digestive conditions. However, the general consensus is that omeprazole is a more potent drug than famotidine.

Randomized, clinical trials have shown that PPIs are more effective in treating duodenal ulcers than H2 blockers. PPIs were found to significantly increase ulcer healing compared to H2 blockers. No significant differences were found between the PPIs that were studied, which included Prevacid lansoprazole , Protonix pantoprazole , and Aciphex rabeprazole. In people who take blood thinners, such as clopidogrel and aspirin, a PPI or H2 blocker can be used to prevent ulcers.

One systematic review found that PPIs were superior to H2 blockers in preventing gastric ulcers. The studies in the review mostly compared Prilosec omeprazole or Nexium esomeprazole with Pepcid famotidine or Zantac ranitidine. The more effective drug is ultimately the one that works best for your condition. Sign up for Omeprazole price alerts and find out when the price changes!

Most Medicare Part D plans and other insurance plans will cover generic famotidine tablets. Try the SingleCare prescription coupon card. Omeprazole delayed-release capsules are covered by most Medicare and insurance plans.

For generic omeprazole capsules, you can use a SingleCare coupon card to lower this cost. The most common side effects of famotidine and omeprazole are headache, dizziness, constipation, and diarrhea. Other gastrointestinal side effects are common and include stomach ache, nausea, and vomiting.

Omeprazole can also cause flatulence or gas. Serious side effects include allergic reactions to any of the ingredients in these medications. Allergic reactions can include rash or trouble breathing. Seek medical attention if you experience serious adverse effects. This may not be a complete list. Consult your doctor or pharmacist for possible side effects. Source: DailyMed famotidine , DailyMed omeprazole.

Famotidine primarily interacts with drugs that depend on stomach acid for absorption. These drugs include antiretrovirals, such as atazanavir and rilpivirine, and antifungals, such as ketoconazole and itraconazole. Taking famotidine can decrease the absorption of these drugs and decrease their overall effectiveness. Ketoconazole coupons What is Ketoconazole? Itraconazole coupons What is Itraconazole? Famotidine can also interact with tizanidine, a muscle relaxer that is processed by the CYP1A2 enzyme in the liver.

Famotidine can increase levels of tizanidine in the body which can lead to low blood pressure hypotension , slow heartbeat bradycardia , or extreme drowsiness. Omeprazole also interacts with some antiretroviral medications, which can lead to a decrease in their effectiveness. These drugs may include tacrolimus and rifampin, among other drugs. Omeprazole can interact with warfarin and increase the risk of abnormal bleeding.

Taking omeprazole with an immunosuppressant called methotrexate can lead to methotrexate toxicity. This may not be a complete list of all possible drug interactions. Consult a doctor with all the medications you may be taking.

Severe GERD symptoms or ulcers may be a sign of gastrointestinal cancer in some people. Famotidine should be used with caution in elderly people or those with kidney problems. Famotidine use can lead to an increased risk of CNS central nervous system adverse effects such as confusion, delirium, and hallucinations. Omeprazole tends to have more warnings and precautions associated with it compared to famotidine.

Unlike famotidine, omeprazole and other PPIs can increase the risk of osteoporosis and bone fractures when used long term. Omeprazole use, especially in a hospital setting, may lead to an increased risk of Clostridium difficile related diarrhea. One study found that proton pump inhibitors are associated with more risks of serious adverse effects like pneumonia and C.

The study took data from 71 hospitals and assessed PPI and H2-blocker use in a specific population of patients. Famotidine is an H2 blocker medication that is used to treat GERD, duodenal ulcers, and stomach ulcers. The efficacy of acid-suppressive drugs for non-erosive gastro-oesophageal reflux disease in Japan, in which the prevalence of Helicobacter pylori infection is higher compared with Western countries, is unknown.

Aim: To compare the efficacy of famotidine and omeprazole in Japanese patients with non-erosive gastro-oesophageal reflux disease by a prospective randomized multicentre trial. Methods: A total of 98 patients received either famotidine 20 mg b. Frequency of gastro-oesophageal reflux disease symptoms and health-related quality of life were evaluated at baseline and after 4 weeks of treatment.

Complete relief was defined as no gastro-oesophageal reflux disease symptoms during the 7-day interval in week 4.